Biology

Biology, Medicine

Ozempic, Wegovy, and Their Promise for Treating Alcohol-Use Disorder

By Carolyn Cao ’28 Over the past few years, Ozempic and Wegovy have become incredibly popular, being used as a “short-cut” for weight loss with prominent public figures like Elon Musk and Andy Cohen promoting it. Though Ozempic and Wegovy were originally created to help treat type 2 diabetes and obesity, new studies indicate that there may be some unintended positive benefits; both may reduce alcohol cravings in people with Alcohol Use Disorder, or AUD. Ozempic and Wegovy work via their active ingredient, semaglutide, which is highly similar to natural hormone GLP-1, having over 90% sequence homology. (GLP-1 regulates appetite and insulin production in the body.) Due to this  structural similarity, semaglutide functions in the human body just like GLP-1: it acts as a GLP-1 ...
Biology, Medicine

Therapy Dogs Bring Healing and Comfort to the Emergency Room

By Ellie Su ’28 A recent study showcased the impressive capacity of therapy dogs to calm anxiety within stressful emergency room environments. In a recent publication, the presence of therapy dogs decreased the anxiety of both children and parents in pediatric emergency departments. In a recent publication led by senior health investigator Jessica Chubak and colleagues, nearly half of the patients who interacted with therapy dogs observed a substantial diminishment of anxiety, and more than 40% of participants reported a significant improvement in general well-being (Chubak et al., 2024). Though the concept of bringing therapy dogs directly into medical settings may sound unorthodox, science tells us there are strong biological and psychological factors at work. How T...
Biology

Reviving the Woolly Mammoth Through Mice

By Alyssa Gu ’28 Contrary to popular belief, woolly mammoths, the famous prehistoric behemoths, coexisted with human beings for thousands of years and only became extinct around 4,000 years ago. The possibility of bringing back woolly mammoths from extinction has become more realistic thanks to recent scientific advances and discoveries of the mammoths’ well-preserved remains. Woolly mammoths had a profound impact on the environment during their existence in the Arctic Tundra. They prevented the spread of trees and tall plants with their heavy footsteps, allowing grasses and shorter vegetation to thrive; these grasslands were more carbon-absorbent than their forest and wetland counterparts. As a result, mammoths’ movements across the landscape maintained and promoted biodiversity. ...
Biology, Medicine

An Introduction to Stem Cells: Why Are They So Important?

By Grace Zheng ’28 What are Stem Cells? Stem cells are one of the most fascinating types of cells. Stem cells are undifferentiated cells, which do not have a specific function or any specialized structures. They are essential for growth, repair, and regeneration. Stem cells have the ability to develop, or differentiate, into specialized cells, and they can also reproduce themselves. This plethora of unique abilities is the reason why stem cells are a very popular topic of research among today’s medical scientists. Stem Cell Classifications In biology, differentiation is when unspecialized cells become specialized for a specific purpose. For example, an undifferentiated stem cell could differentiate into a skin cell. Therefore, stem cells can be classified by their differentiati...
Biology

Humans Are The Biggest Threat to Frog Biodiversity

By Eric Yang ’28 Amphibian species are today considered by biologists at Harvard the vertebrate class most threatened by the onslaught of climate change and various other factors, with 2 out of every 5 amphibians facing extinction. Climate change, a largely man-made crisis, is the main culprit for these problems, particularly its role in creating devastating droughts. With so much land and potential frog habitats being destroyed in favor of agriculture, frogs and other amphibians are already contending with limited space and resources to survive. Droughts are especially catastrophic, as frogs need to stay moist in order to absorb water and thus the oxygen they need to breathe. However, oxygen intake through a frog’s skin is equally useless if the body of water a frog occupies doesn’t...
Biology, Technology

Introducing RenewBlue: PASC’s Newest Project-Led Initiative

By Claire Bancroft '28 This year, the Phillips Academy Sustainability Coalition (PASC) welcomes an exciting new initiative: RenewBlue, a club aimed at developing practical, hands-on climate solutions. In contrast to the previous PASC initiatives, Matt Robinson and Henry Zimmerman wanted to bridge the gap between environmental discussion and physical action: “It [RenewBlue] came out of a lack of practical solutions. We were thinking that we wanted a place at PASC where people could actually make things and do physical activities, instead of either thinking or talking about solutions. That’s how it came about!”says founding member Matt Robinson. Despite having a slower start in October, RenewBlue quickly gained momentum. When asked about the projects in the club, Robinson mentioned the...
Biology, Technology

The Unquenchable Thirst of Artificial Intelligence: Data Centers and their Water Consumption

By Alex Lin '28 It’s no secret that the AI industry is exploding. The generative AI market alone is projected to increase to $1 trillion USD in 2032, and the physical AI infrastructure, temperature-controlled buildings known as data centers, is estimated to almost double worldwide by 2030. Amidst the rapid development of artificial intelligence (AI) and an utter lack of transparency within the competitive industry,  researchers and policy makers are scrambling to determine what impact their expansion has on the environment: their need for both massive and stable amounts of power, inequity concerns, heat and noise pollution, and water consumption.  According to the Environmental and Energy Study Institute, large data centers can consume up to 5 million gallons of water daily...
Biology, Technology

Scientists Combating Climate Change by Genetic Modification

By Paxton Auguste '28 The agricultural industry is responsible for one-third of global greenhouse gas emissions. These greenhouse gases trap heat in the Earth’s atmosphere, leading to sea level rise, dry soil, more severe weather events, and other abiotic stresses on environments and their plants. Historically, genetic modification has been used to alter the size, yield, behavior, disease and pest resistance of crops and livestock. Scientists are now experimenting with using genetically modified organisms, or GMOs, to help crops combat and adapt to drastic changes in climate. Proteins are crucial to an organism’s functioning; each gene in an organism provides instructions on how to make a certain protein. Transcription factors are proteins that bind to specific DNA sequences and regu...
Biology, Technology

Cultivating the Future of Sustainable Agriculture

By Manalee Chowdhury '28 Agriculture has begun to transition from rows of people working fields to a coordinated system of machines: robots on the ground, drones in the air, and automated algorithms making decisions in between. This transition reflects mounting pressure from rising labor costs, worker shortages, and increasing food demand globally. As detailed in the Agricultural Drone Industry Report, the industry is integrating Artificial Intelligence (AI) and the Internet of Things into the core of food production to ensure survival in an era of climate volatility. On the ground, agricultural robots are increasingly handling specific repetitive tasks like harvesting, identifying weeds, or navigating fields using computer vision. These machines rely on combinations of sensors, moti...
Biology, Technology

Date of Cambrian Explosion Thrown Into Doubt by New Fossil Discoveries

By Amara Muller '29 What if one of evolution’s most famous events didn’t happen when scientists thought it did? For decades, most scientists believed that complex life on Earth arose through the Cambrian Explosion, a sudden burst of rapid evolution beginning around 535 million years ago; this diversification of life led to many of the organism groups we see today. However, recent fossil discoveries in China are challenging this narrative. If these new findings prove to be accurate, complex life’s origins may stretch back millions of years before previously thought, and the ‘explosion’ theory may require more nuance than before. The Transitions Heralded by the Cambrian Period Before the Cambrian Period spanned the Ediacaran Period, lasting from 635 to 541 million years ago. The maj...